23. FRASIER 

Created by David Angell & Peter Casey & David Lee, Based on the character "Frasier Crane" created by Glen Charles & Les Charles  

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Aired: NBC, 1993-2004

The Grub Street Productions team of Casey-Angell-Lee furthered the work they’d done on Cheers by moving psychologist Frasier Crane from Boston to Seattle and giving him a radio call-in show. In the process, the writer-producer trio created the last great spin-off. The pleasure in watching Frasier was in the repartee between Frasier (Kelsey Grammar) and his brother Niles (David Hyde Pierce), an equally cultured effete snob. Their banter provided the fizz in a cocktail that included John Mahoney as their retired cop father and Jane Leeves as his home health-care aid de camp. “We hit upon this idea of doing something we didn’t think we’d be good at, which was doing a family comedy,” David Lee said, of the show’s origins. “We thought we were just gang comedy writers.”

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